RML emerged from Naut Humon's lifetime of performance format exploration and cross-media co-operations. After migrating to the San Francisco region in the early seventies, Humon and his young teenage associates actualized a series of audience mobilization and transport events that moved the engaged spectators through various indoor/outdoor sites such as factories, poly-room buildings, caves, abandoned warehouses, sensory deprivation environments, weather chambers, and heavily customized theatre venues during multiple dozens of staged events. 

Recombinant Media Labs is the result of experiments that started over three decades ago with the corroded Sound Traffic Control tower of tube television stacks amidst hundreds of speaker arrays in Tokyo's Ginza district. After a number of years of blending live vs. programmed events of symphonic scale and substance, RML and Asphodel, an independent record label, joined forces to occupy two fixed-location depots in the California Bay Area to head-quarter a performance-residency center for developing their simulation style of surround cinema. After working for several years in a fixed location within the central city of San Francisco, a new organization with a focus on developing mobile global festival setups was founded. Over the years Recombinant Media Labs has built up a selected resource of residency artworks and it was time to highlight this advancing body of AV pieces out to the rest of the world. Freed from the constraints of a geographically anchored construction, RML’s nomadic approach is also able to offer residencies together with organizations in metropolitan locations. This vanguard hybrid media platform encompasses many presentational options to potential partners, (co)-producers, and curators.  
   
The code 'recombinant' in Recombinant Media Labs is a term taken from the field of genetics. Springing out of this spatial media synthesis grid is a process that simulates the incubation of a recombinant organism in the form of electronic 'offspring' that comes to possess cultural, mutational characteristics that didn’t necessarily exist in either 'parent'. 
  
Recombinant Media Labs has developed partnerships with the Center for Research in Computing and the Arts (CRCA) at University of California at San Diego (UCSD), The ECAS (European Cities of Advanced Sound), and the ICAS (International Cities of Advanced Sound & Media ) networks. 

Naut Humon has been the conductor & catalyst for the annually held Recombinant Festival and RMLCineChamber, Asphodel Records, and AV curator for select portions of the annual Prix Ars Electronica Festival in Austria where he also chaired the American co-ordinations in their Digital Musics and Sound Art category for a full decade.